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I just started taking the pills again after taking a break over xmas, and within a week I had all the side effects back. Funny thing is that I had been feeling sick back in Nov and even went to the Dr's twice complaining of ear aches and chest pain they checked me out even did an EEG and said they couldn't find anything wrong with me. Also about the same time my wife thought I seemed depressed (I'm never depressed) but when I thought about it I had symtoms of depression (never felt depressed though). I stopped taking xenical just before xmas, we went away and I found it easier not to take it during the holiday. I just started back on it a 2 weeks ago and after about a week I noticed first a bad headache then chest pain, searched the net and couldn't find similar side effect. next day I noticied my ears kind of hollow and sore decided to stop taking it, all symtoms are gone except ears still a little sore (but they took about a week to stop aching at xmas). I finally had some time tonight to look for a forum and I see others are also having side effects. Anyway I'm done with Xenical it never really worked that well for me anyway as I discovered fats not my problem carbs are. I did lose a few pounds well on it but I find I can lose just as easily if I watch my bread and potato and pasta intake.